Waa kuwee habka ugu wanaagsan?
-Waxaa loogu talagalay baaritaanka cudurka SARS-2
Xaaladaha aadka u gaarka ah ee la xaqiijiyay ee la xaqiijiyay ee la xaqiijiyay Daalada-19aad, ayaa soo sheegay astaamaha guud ee rugaha caafimaad ee caamka ah waxaa ka mid ah qandho, qufac, MyLia ama daal. Laakiin astaamahaas ma aha astaamo u gaar ah oo ah dovid-19 maxaa yeelay astaamahan waxay la mid yihiin cudurada kale ee cudurka fayraska ku dhaca sida hargabka. Xilligan, fayraska nucleic acid ee PCR (RT-PCR), sawirka CT iyo qaar ka mid ah cabirrada heatrogy waa aaladaha aasaasiga ah ee ogaanshaha caafimaad ee cudurka. Xirmooyin tijaabo ah oo sheybaarka ah ayaa la sameeyay oo loo adeegsaday tijaabinta muunadda bukaanka ee loogu talagalay qaddarka '19' oo ay sameeyeen CDC Shiinaha1, US CDC2iyo shirkadaha kale ee gaarka loo leeyahay. IGG / Habka Imtixaanka IGM, ayaa sidoo kale lagu daray shuruudaha ogaanshaha nooca cusboonaysiinta ee ku saabsan cudurka 'chinavirus' ee cudurka cronavirus (doonovirus-19), oo ah 3-da Maarso1. Fayraska Nucleic acid Acid ee RT-PCR-PCR wali waa habka caadiga ah ee baaritaanka caadiga ah ee lagu ogaado cudurka dovid-19.
La jeedasho®Sheeko-sheeko (SARS-Cov-2) BILAASH TILMAAMAHA MADAXWEYNAHA PCR-ga
Laakiin xirmooyinka tijaabada ah ee PCR-yada ee waqtiga-dhabta ah, raadinta maaddada hidda-wadaha ee fayraska, tusaale ahaan sanka, afka, afka, ama suufka dabada ah, waxay la ildaran yihiin xaddidaadyo badan:
1) Tijaabadaasi waxay leeyihiin waqtiyo dhaadheer oo istaaga ah oo ay adag yihiin howlgalka; Waxay guud ahaan qaataan celcelis ahaan 2 ilaa 3 saacadood si ay u soo saaraan natiijooyin.
2) Tijaabada PCR-da waxay u baahan tahay sheybaar shahaado leh, qalab qaali ah iyo farsamoyaqaanno tababaran oo tababaran.
3) Waxaa jira dhowr tirooyin diidmo been ah oo loogu talagalay RT-PCR oo ah boopid-19. Waxaa laga yaabaa inay sabab u tahay SARS-COV-2 ee rarka fayraska ee Shupimun-ka sare ee cronavirus-ka ee sare (cronavirus-ka sare ee cronavirus-ka) (Sawirka 'pronavirus-ka sare' ayaa inta badan ku dhaca marinka neef-mareenka hoose, sida alveroli-ka sambabka ee hoose) oo baaritaanka ma garan karo dadka soo maray infekshan, dib loo soo celiyo, iyo ka nadiifi fayraska jirkooda.
Cilmi baarista Lirong Zou et al4Waxaa la ogaaday in xamuulkii fayras sare la helay kadib calaamadaha cudurka, oo leh xamuul fayri ah oo sanka laga helo marka loo eego hunguriga aaladda ee burooyinka ah ee ku dhaca SARS-Coves-ka ah4oo u muuqata mid ka duwan kan ku arkay bukaannada qaba SARS-Cov-2.
Yang pan et al5Baadhitaannada Serial (Swabs hunguriga, kaararka hunguriga, kaadida, kaadida, iyo saxarada) laba bukaan ah oo ku yaal tuubbada hunguriga iyo swspings offs swssens-ka dib-u-dhaca, samballada xaako ah ayaa guud ahaan muujiyey xamuul fayras badan Saamiyada cunaha. Wax fayl virus ah ayaa lagu ogaadey kaadida ama kaadida saxarada ee labadan bukaan ah.
Tijaabada PCR kaliya bixi kaliya natiijo wanaagsan marka fayrasku wali joogo. Imtixaannada ma garan karaan dadka soo maray caabuqa, dib loo soo kabsaday, waxayna ka nadiifiyeen fayraska jirkooda. Dhaqdhaqaaq ahaan, kaliya 30% -50% waxay u fiicneyd PCR bukaan-jiifka ah ee bukaanka qaba cudurka 'coronavirus' oo caafimaad. Qaar badan oo ka mid ah bukaanka 'coronavirus' oo ah pneumonia pneumonia lama ogaan karo sababta oo ah baaritaanka nucleic ee xun, si aysan u helin daaweynta u dhiganta waqtiga. Laga soo bilaabo markii ugu horreysay ee daabacaadda lixaad ee tilmaamaha, ku tiirsanaanta kaliya natiijada natiijooyinka baaritaanka nucleic acid, kaas oo sababay dhibaato weyn oo ku saabsan dhakhaatiirta rugta caafimaadka, ee 'Li Wenliang', ophthalmalmoff Isbitaalka, ayaa dhintay. Intii uu noolaa, wuxuu lahaa saddex imtixaanno ashtious nucleic ah kiiska qandhada iyo qufaca, iyo markii ugu dambeysay ee uu helo natiijooyin wanaagsan oo PCR ah.
Ka dib wada hadalka ka dib khabiiro, waxaa la go'aansaday in la kordhiyo hababka imtixaanka Serum sida shuruud lagu ogaado cudurka ogaanshaha. In kasta oo tijaabada ka hortagga ka hortagga ah, oo sidoo kale loo yaqaanno tijaabooyinka serogiy, taasi waxay xaqiijin kartaa inuu qof cudurka qabo xitaa in la nadiifiyo nidaamka jirridda difaaca jirkooda uu nadiifiyo fayraska sababa dovid-19.
Hardstep® SARS-Cov-2 IGG / IGM Antibod Darawadda Degdegga
Tijaabada IGG / IGM waxay gacan ka geysan doontaa raadinta hab ku saleysan dadka ku saleysan cudurka, maxaa yeelay kiisas badan ayaa u muuqda inay ku faafto bukaannada asymptomatic-ga ee aan si fudud loo aqoonsan karin. Lammaane ku nool Singapore, ninku wuxuu tijaabiyay PCR-da PCE, natiijada xaaskiisa ee xaaskiisa PCR, laakiin natiijooyinka baaritaanka ka hortaga ee ka hortaga ayaa muujiyay in ay leedahay difaac, sida ninkeeda.
JeroloLs assyyss waxay u baahan tahay in si taxaddar leh loo ansaxiyo si loo hubiyo inay falceliyaan si kalsooni leh, laakiin kaliya unugyada ka hortagga ah ee ka dhanka ah fayraska sheekada. Hal walaac ayaa ka mid ahaa in la mid ah kuwa u dhexeeya fayrasyada sababa cudurka neef-mareenka neefsashada oo daran iyo sadarka ba'an-19 ay horseedi karto is-dhaafsiisi. IGG-IGM wuxuu soo saaray Xee Feng Wang6Waxaa loo tixgeliyaa in loo istcimaalo tijaabo daryeel-taxaddar ah (poct), maadaama lagu sameyn karo meel u dhow sariirta sariirta. Xirku wuxuu leeyahay xasaasiyad 88.66% iyo gaar ahaaneed 90.63%. Si kastaba ha noqotee, wali waxaa jiray natiijooyin been abuur ah oo been ah oo been ah.
Nooca la cusbooneysiiyay ee Shiinaha ee baaritaanka iyo tilmaamaha daaweynta ee cudurka 'coronavirus' (doovid-19)1, kiisaska la xaqiijiyay waxaa lagu qeexay sidii kiisaska looga shakisan yahay ee la kulma mid ka mid ah shuruudahan soo socda:
(1) Tijaabada kaadida neef-mareenka, dhiigga ama muunadaha saxarada ama saxarada saxarada waxay tijaabiyeen togan ee SARS-2 acid Nucleic acid iyadoo la adeegsanayo RT-PCER;
(2) Isku-darka hidaha ee fayraska ka yimaada mareenka neef-mareenka, dhiigga ama muunadaha saxarada muunadaha ayaa ah mid aad u horumarsan SARS-yada la yaqaan ee SARS-Cov-2;
(3) Serum Cus Corronavirus Gaarka ah ee CORONAVIRUS ee IGM Antibody iyo IGG ka hortag ayaa ahaa kuwa togan;
(4) Serum Cutubka Cronavirus-Gaar ah ee Igg Antibody wuxuu ka yimid taban taban ama taban ee Igg-Cronaviroos-ka inta lagu jiro muddada soo kabashada ayaa 4 jeer ka sareeya tan inta lagu jiro xilligaas inta lagu jiro xilligaas.
Cudurka ogaanshaha iyo daaweynta qaraabada-19
| Xeer-degan | Masaydh | Aasaaska ogaanshaha cudurka |
| Nooca 7aad | 3MAR.2020 | ❶ pcr ❷ ngs ❸ Igm + Igg |
| Nooca 6aad | 18 Feb.2020 | ❶ pcr ❷ ngs |
Qoraal ka warbixineya
1. Tilmaamaha cudurka ogaanshaha iyo daaweynta 'coronavirus' oo ah pneumonia (Coronavirus-ka 'Coronavirus'
http://www.nhc.gov.cn/yzygj/s7652m/202003/a311444421421421444b984bf980bfed5579d5sl
2. Cilmi baarista oo keliya oo keliya oo loo yaqaan 'rt-pr-PCR-PCR-PCR' ee loo aqoonsado aqoonsiga 2019-Ncov
https://www.cdc.gov/coronavirus/2019-ncov/lab/lt-cccention-intsites.html
3. Singapore wuxuu sheeganayaa in ugu horeysa ee loo isticmaalo baaritaanka ka hortagga ah si loo raaco caabuqyada coronavirus
https://www.sciencemag.org/news/2020/02/singapore-claims-first-use-antibody-test-track-coronavirus-infections
4.Sar-Cov-2 rar viral-ka ah muunadaha neefsashada ee sare ee bukaanka cudurka qaata Febraayo 19,2020 Doi: 10.106 / nejmc2001737
5.Virallods of SARS-Cov-2 ee sambalooyinka bukaan-jiifka Lancket Nancet Nafaqo-qaad Nan 2020 Waxaa la daabacay khadka Febraayo 24, 2020 (https://doi.org/10.373-309930)30)30)30)30)30)
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Cillada cudurka Infekshanka Xeefeng Wang Orcid Orciid ID: 0000-0001-8854-275x
Waqtiga Post: Mar-17-2020
