Hal adduun hal dagaal
─Iskaashiga caalamiga ah si loo dhiso bulsho caalami ah oo masiirka guud ah oo ka jawaabaya caqabadaha faafa ee COVID-19
Faafida cusub ee loo yaqaan 'coronavirus' ee ku faafay adduunka oo dhan waxay keentay xiisadda faafa ee COVID-19 ee caalamiga ah ee socota.Sheekada coronavirus-ku ma laha xuduud, waddanna kama badbaadi doono dagaalkan lagula jiro COVID-19.Iyada oo laga jawaabayo masiibadan caalamiga ah ee COVID-19, Liming Bio-Products Corp waxay samaynaysaa tabarucaad si ay u taageerto wanaagga bulshooyinkayada caalamka.
Dunideenu hadda waxa ay wajahday saamaynta aan hore loo arag ee cudurka coronavirus-ka cusub ee 2019 (COVID-19) ee faafa.Ilaa hadda, ma jirto daawo wax ku ool ah oo loo heli karo daaweynta cudurkan.Si kastaba ha ahaatee, baaritaano badan oo ogaanshaha ayaa loo sameeyay si loo ogaado COVID-19.Tijaabooyinku waxay ku salaysan yihiin hababka molecular ama serological si loo ogaado novel coronavirus nucleic acid ama biomarkers antibody.Maaddaama COVID-19 uu gaaray heer masiibo ah, ogaanshaha hore ee caabuqa coronavirus-ka cusub ayaa muhiim u ah qiimeynta faafitaanka fayraska iyo ka koobntiisa, laakiin tijaabada saxda ah ee isticmaalka caalamiga ah wali ma jiro.Waa inaan ogaano shaybaadhoyinka suurtagalka ah ee loo isticmaali karo baadhista, ogaanshaha, iyo la socodka caabuqa COVID-19, iyo maxay yihiin xaddidaaddooda.Aad bay muhiim u tahay sida si wanaagsan looga faa'iidaysan karo qalabkan cilmiyeed iyo in gacan laga geysto ogaanshaha iyo xakameynta soo ifbaxa cudurkan sida degdega ah u faafaya ee halista ah.
Ujeedada ogaanshaha cudurka 'coronavirus' cusub waa in la go'aamiyo in qofka qaba caabuqa COVID-19 ama side asymptotic oo laga yaabo inuu si aamusan u faafiyo fayraska, si loo bixiyo macluumaadka muhiimka ah si loo hago go'aan qaadashada daaweynta bukaan-socodka.Daraasado hore ayaa muujiyay in 70% go'aamada caafimaadku ay ku xiran yihiin natiijooyinka baaritaanka.Marka hababka ogaanshaha kala duwan la isticmaalo, shuruudaha xirmooyinka reagent ogaanshaha sidoo kale waa kala duwan yihiin.
sawirka 1
Jaantus1:Jaantuska muujinaya heerarka muhiimka ah ee heerarka biomarker-ka guud inta lagu jiro muddada caadiga ah ee caabuqa COVID-19.dhidibka X waxa uu tilmaamayaa tirada maalmaha caabuqa, dhidibka Y-na waxa uu tilmaamayaa culayska fayraska, xoojinta antigens, iyo xoojinta unugyada difaaca ee xilliyo kala duwan.Ka-hortagga difaaca jirka waxaa loola jeedaa IgM iyo IgG-ka-hortagga unugyada.Labada RT-PCR iyo ogaanshaha antigen waxaa loo isticmaalaa in lagu ogaado jiritaanka ama maqnaanshaha coronavirus-ka cusub, taas oo caddayn toos ah u ah ogaanshaha bukaanka hore.Usbuuc gudihiis ee caabuqa fayraska, ogaanshaha PCR, ama ogaanshaha antigen ayaa la door bidaa.Ka dib infekshanka coronavirus-ka cusub ee ku saabsan 7 maalmood, antibody-ka IgM ee ka dhanka ah coronavirus-ka cusub ayaa si tartiib tartiib ah ugu kordhay dhiigga bukaanka, laakiin muddada jiritaanku waa mid gaaban, oo diiradda saaraya si dhakhso ah ayey u yar tahay.Taas bedelkeeda, IgG-ga ka-hortagga fayraska ayaa soo muuqda mar dambe, badanaa qiyaastii 14 maalmood ka dib infekshanka fayraska.Diiradda IgG ayaa si tartiib tartiib ah u kordheysa, waxayna ku sii jirtaa dhiigga muddo dheer.Sidaa darteed, haddii IgM laga helo dhiigga bukaanka, waxay la macno tahay in fayrasku uu dhawaan qaaday, kaas oo ah calaamad hore oo caabuq ah.Marka difaaca IgG laga helo dhiigga bukaanka, waxay la macno tahay in caabuqa fayrasku uu jiray muddo.Waxa kale oo loo yaqaan infekshan dambe ama caabuq hore.Waxaa badanaa lagu arkaa bukaanada ku jira marxaladda soo kabashada.
Biomarkers-ka novel coronavirus
Novel coronavirus waa fayras RNA, oo ka kooban borotiinno iyo asiidhyo nucleic ah.Fayrasku waxa uu ku soo duulaa jidhka martida loo yahay ( bini'aadamka ) , waxa uu unugyada ka galaa iyada oo la isku xidho goobta u dhiganta reseptor-ka ACE2, oo uu ku celceliyo unugyada martida loo yahay, taas oo keenta in habka difaaca bini'aadamku uu uga jawaabo soo duulayaasha shisheeye oo uu soo saaro unugyada difaaca gaarka ah.Sidaa darteed, vial nucleic acids iyo antigens, iyo unugyada gaarka ah ee ka hortagga coronavirus-ka cusub ayaa aragti ahaan loo isticmaali karaa sidii biomarkers gaar ah si loo ogaado cudurka 'coronavirus' cusub.Helitaanka aashitada nukliyeerka, tignoolajiyada RT-PCR ayaa ah tan ugu badan ee la isticmaalo, halka hababka serological inta badan loo isticmaalo ogaanshaha unugyada cusub ee ka hortagga coronavirus-ga gaarka ah.Hadda, waxaa jira habab kala duwan oo baaritaanno ah oo diyaar ah oo aan dooran karno si loo baaro caabuqa COVID-19 [1].
Mabaadi'da aasaasiga ah ee hababka baaritaanka ugu weyn ee coronavirus-ka cusub
Tijaabooyin badan oo lagu ogaanayo COVID_19 ayaa diyaar ah ilaa hadda, iyada oo qalabyo shaybaadho badan ay helayaan oggolaansho iyadoo la raacayo oggolaanshaha isticmaalka degdegga ah maalin kasta.In kasta oo horumarka cusub ee tijaabada ah uu ku soo baxayo magacyo iyo qaabab kala duwan, dhammaan tijaabooyinka COVID_19 ee hadda jira waxay asal ahaan ku tiirsan yihiin laba teknooloji oo waaweyn: ogaanshaha aashitada nukliyeerka ee fayraska RNA iyo immunoassays serological oo lagu ogaanayo ka-hortagga fayraska-gaarka ah (IgM iyo IgG).
01. Ogaanshaha Nucleic acid
Falcelinta silsiladda-polymerase-ka-noqoshada (RT-PCR), amplification isothermal dhexdhexaadin loop-dhexdhexaadin ah (LAMP), iyo taxanaha jiilka soo socda (NGS) waa hababka caadiga ah ee aashitada nukliyeerka ee lagu ogaanayo novel coronavirus RNA.RT-PCR waa nooca ugu horreeya ee baaritaanka COVID-19, oo ay ku taliyaan labadaba Ururka Caafimaadka Adduunka (WHO) iyo Xarunta Xakamaynta iyo Kahortagga Cudurrada ee Maraykanka (CDC).
02.Serological antibody ogaanshaha
Antibody waa borotiin difaac ah oo laga soo saaro jidhka bini'aadamka si looga jawaabo caabuqa fayraska.IgM waa nooc hore oo ka hortag ah halka IgG uu yahay nooca dambe ee antibody.Muunada serum ama balaasmaha waxaa badanaa laga baaraa jiritaanka IgM gaar ah iyo noocyada IgG ee kahortaga jirka si loo qiimeeyo wejiyada ba'an iyo kuwa ka soo kabanaya caabuqa COVID-19.Hababkan ogaanshaha ku salaysan ka-hortagga jidhka waxaa ka mid ah baaritaanka immunochromatography ee kolloidal, cinjirka ama fluorescent microsphere immunochromatography, enzyme-linked immunosorbent assay (ELISA), iyo chemiluminescence assay.
03.In la ogaado antigen-ka fayraska
Antigen-ku waa qaab-dhismeedka fayraska uu aqoonsan yahay jidhka bini'aadamka kaas oo kiciya habka difaaca difaaca si uu u soo saaro unugyada difaaca si uu fayraska uga nadiifiyo dhiigga iyo unugyada.Antigen-ka fayrasku ku jiro ee fayraska waa la bartilmaameedsan karaa oo lagu ogaan karaa iyadoo la isticmaalayo immunoassay.Sida fayraska RNA, antigens-ka fayraska ayaa sidoo kale ku jira mareenka neef-mareenka ee shakhsiyaadka cudurka qaba waxaana loo isticmaali karaa in lagu ogaado wejiga degdega ah ee caabuqa COVID-19.Sidaa darteed, waxaa badanaa lagu taliyaa in la ururiyo shaybaarrada neef-mareenka sare sida candhuufta, naasopharyngeal iyo suufka oropharyngeal, xaako qoto dheer, dheecaanka bronchoalveolar lavage (BALF) ee baaritaanka antigen-ka bilowga ah.
Doorashada hababka baaritaanka coronavirus-ka cusub
Doorashada habka imtixaanku waxay ku lug leedahay arrimo badan, oo ay ku jiraan goobta bukaan-socodka, xakamaynta tayada tijaabada, wakhtiga soo celinta, kharashyada tijaabada, muunad hababka ururinta, shuruudaha farsamada shaqaalaha shaybaadhka, xarunta iyo shuruudaha qalabka.Ogaanshaha asiidhka nucleic ama antigens-ka fayraska waa in la bixiyo caddayn toos ah oo ku saabsan jiritaanka fayrasyada iyo in la xaqiijiyo ogaanshaha caabuqa cusub ee coronavirus.In kasta oo ay jiraan habab badan oo lagu ogaanayo antigen-ka, ogaanshaha dareenkooda ee coronavirus-ka cusub ayaa aragti ahaan ka hooseeya kan kor-u-qaadista RT-PCR.Baaritaanka difaaca jirka waa ogaanshaha unugyada difaaca jirka ee ka hortagga fayraska ee laga soo saaro jirka bini'aadamka, kaas oo dib u dhacaya waqti badan oo aan badanaa loo isticmaali karin in la ogaado goor hore inta lagu jiro marxaladda degdega ah ee caabuqa fayrasku.Goobta daawaynta ee codsiyada ogaanshaha way kala duwanaan kartaa, goobaha muunada ururinta sidoo kale way kala duwanaan karaan.Si loo ogaado asiidhyada nucleic-ka ee fayraska iyo antigens-ka, muunadda ayaa loo baahan yahay in lagu soo ururiyo mareenka neef-mareenka halkaas oo fayrasku ku jiro, sida suufka nasopharyngeal, suufka oropharyngeal, xaako, ama dheecaanka bronchoalveolar lavage (BALF).Ogaanshaha ka-hortagga-ku-saleysan-ahaaneed, muunadda dhiigga ayaa loo baahan yahay in la ururiyo oo laga baaro joogitaanka anti-virus gaar ah (IgM/IgG).Si kastaba ha ahaatee, natiijooyinka baaritaanka antibody iyo nucleic acid ayaa midba midka kale kaabi kara.Tusaale ahaan, marka natiijadu tahay nucleic acid-negative, IgM-negative laakiin IgG-positive, natiijooyinkani waxay muujinayaan in bukaanku aanu hadda qaadin fayraska, laakiin laga soo kabsaday caabuqa coronavirus-ka cusub.[2]
Faa'iidooyinka iyo khasaarooyinka baarista coronavirus-ka cusub
Xeerka ogaanshaha iyo daawaynta ee Novel Coronavirus Pneumonia (Trial Version7) (Waxa soo saaray Komishanka Caafimaadka Qaranka & Maamulka Gobolka ee Daawada Dhaqanka Shiinaha Maarso 3, 2020), baadhista aashitada nukliyeerka waxaa loo isticmaalaa habka heerka dahabka ee ogaanshaha sheekada infekshanka coronavirus, halka baaritaanka antibody-ka sidoo kale loo tixgeliyo mid ka mid ah hababka xaqiijinta ee ogaanshaha.
Natiijooyinka cudur-sidaha iyo serological
(1) Natiijooyinka cudur-sidaha: Novel coronavirus nucleic acid waxaa lagu ogaan karaa suufka sanka, xaakada, dheecaannada mareenka neef-mareenka hoose, dhiigga, saxarada iyo muunado kale iyadoo la adeegsanayo hababka RT-PCRand/ama NGS.Way saxsan tahay haddii muunadaha laga helo mareenka neef-mareenka hoose (xaakada ama soo saarista hawada).Tusaalooyinka waa in loo gudbiyaa si loo tijaabiyo sida ugu dhakhsaha badan ee suurtogalka ah ka dib ururinta.
(2) Natiijooyinka serological: NCP fayraska gaarka ah IgM wuxuu noqdaa mid la ogaan karo 3-5 maalmood ka dib bilawga;IgG wuxuu gaaraa titration ugu yaraan 4-laab ah oo kordhay inta lagu jiro nafisinta marka la barbar dhigo marxaladda ba'an.
Si kastaba ha ahaatee, xulashada hababka imtixaanku waxay ku xiran yihiin goobaha juqraafiyeed, xeerarka caafimaadka, iyo goobaha caafimaadka.Gudaha Mareykanka, NIH waxay soo saartay Cudurka Coronavirus 2019 (COVID-19) Tilmaamaha Daaweynta (Goobta la cusbooneysiiyay: Abriil 21,2020) iyo FDA waxay soo saartay Siyaasadda Baaritaannada lagu ogaanayo Cudurka Coronavirus-2019 inta lagu jiro Xaaladda Degdegga ah ee Caafimaadka Dadweynaha (oo la soo saaray Maarso 16,2020) ), kaas oo baaritaanka serological ee unugyada difaaca jirka ee IgM/IgG loo doortay oo kaliya sidii baadhis baadhis ah.
Habka Ogaanshaha Ashitada Nukliyeerka
RT_PCR waa shaybaadh xasaasi ah oo nucleic acid ah oo loogu talagalay in lagu ogaado in coronavirus-ka cusub ee RNA uu ku jiro neefsiga ama muunado kale iyo in kale.Natiijada baaritaanka PCR ee togan macnaheedu waa joogitaanka novel coronavirus RNA ee muunada si loo xaqiijiyo caabuqa COVID-19.Natiijooyinka baaritaanka PCR ee taban macnaheedu maaha maqnaanshaha caabuqa fayraska sababtoo ah waxaa saameyn kara tayada muunada oo liidata ama waqtiga cudurka marxaladda soo kabsaday, iwm.In kasta oo RT-PCR ay tahay imtixaan xasaasi ah, haddana waxay leedahay cillado dhowr ah.Tijaabooyinka RT-PCR waxay noqon karaan kuwo xoog badan oo waqti badan qaata, oo si aad ah ugu xiran tayada sare ee muunada.Tani waxay noqon kartaa caqabad sababtoo ah qadarka fayras RNA kaliya maaha mid aad u kala duwan inta u dhaxaysa bukaanada kala duwan, laakiin sidoo kale way ku kala duwanaan kartaa isla bukaan-socodka iyadoo ku xiran waqtiyada marka muunada la qaado iyo sidoo kale wejiyada caabuqa ama bilawga calaamadaha kiliinikada.Helitaanka coronavirus-ka cusub wuxuu u baahan yahay muunado tayo sare leh oo ka kooban cadad ku filan oo fayraska RNA ah.
Tijaabada RT-PCR waxay ku siin kartaa natiijo xun oo khaldan (been abuur ah) bukaanada qaar ee qaba caabuqa COVID-19.Sida aan ognahay, meelaha ugu muhiimsan ee caabuqa coronavirus-ka cusub waxay ku yaalliin sambabada iyo mareenka neef-mareenka hoose, sida alveoli iyo boronkii.Sidaa darteed, muunada xaakada ee qufaca qoto dheer ama dheecaanka bronchoalveolar lavage (BALF) ayaa loo arkaa inay leeyihiin dareenka ugu sarreeya ee ogaanshaha fayraska.Si kastaba ha noqotee, waxqabadka kiliinikada, shaybaarada ayaa inta badan laga soo qaadaa mareenka neef-mareenka sare iyadoo la isticmaalayo nasopharyngeal ama suufka oropharyngeal.Soo ururinta muunadahan kuma raaxaysanayso bukaanka oo keliya balse waxay sidoo kale u baahan tahay shaqaale si gaar ah u tababaran.Si muunaddadu u yaraato ama u fududaato, xaaladaha qaarkood bukaanada waxaa laga yaabaa in la siiyo suuf afka ah oo loo oggolaado inay muunad ka soo qaadaan xabka buccal ama carrabka is-xoqeynaya.La'aanta RNA fayraska ku filan, RT-qPCR waxay soo celin kartaa natiijada baaritaanka been-abuurka ah.Gobolka Hubei, Shiinaha, dareenka RT-PCR ee ogaanshaha hore ayaa la soo sheegay kaliya 30% -50%, iyadoo celcelis ahaan 40%.Heerarka sare ee been-abuurka beenta ah waxay u badan tahay inay sababtay muunad aan ku filnayn.
Intaa waxaa dheer, tijaabada RT-PCR waxay u baahan tahay shaqaale aad u tababaran si ay u qabtaan tillaabooyinka soo saarista RNA adag iyo habka kor u qaadida PCR.Waxa kale oo ay u baahan tahay ilaalin sare oo badbaado noolaha ah, xarun shaybaadhka gaarka ah, iyo qalabka PCR ee waqtiga-dhabta ah.Shiinaha, baaritaanka RT-PCR ee ogaanshaha COVID-19 wuxuu u baahan yahay in lagu sameeyo heerka badbaadada noolaha ee 2 shaybaar (BSL-2), iyadoo la ilaalinayo shaqaalaha iyadoo la adeegsanayo dhaqanka heerka badbaadada noolaha 3 (BSL-3).Marka loo eego shuruudahan, laga bilaabo bilowga Janaayo ilaa horraantii Febraayo 2020, awoodda shaybaarka CDC ee Shiinaha Wuhan wuxuu awooday oo keliya inuu ogaado dhowr boqol oo kiis maalintii.Caadiyan, tani dhib ma ahaan doonto marka la baarayo cudurrada kale ee faafa.Si kastaba ha ahaatee, marka lala tacaalayo masiibo caalami ah sida COVID-19 oo ay suurtagal tahay in malaayiin qof la tijaabiyo, RT-PCR waxay noqotaa arrin xasaasi ah sababtoo ah shuruudaha xarumaha shaybaadhka gaarka ah ama qalabka farsamada.Khasaarooyinkan ayaa laga yaabaa inay xaddidaan RT-PCR in loo isticmaalo qalab wax ku ool ah oo lagu baadho, iyo sidoo kale waxay keeni kartaa dib u dhac ku yimaada warbixinnada natiijooyinka imtixaannada.
Habka ogaanshaha antibody-ka serological
Iyadoo horumarka koorsada cudurka, gaar ahaan marxaladaha dhexe iyo dambe, heerka ogaanshaha antibody waa mid aad u sarreeya.Daraasad lagu sameeyay Cusbitaalka Bartamaha Koonfurta ee Wuhan ayaa muujisay in heerka ogaanshaha ka-hortagga jidhku uu gaadhi karo in ka badan 90% toddobaadka saddexaad ee caabuqa COVID-19.Sidoo kale, antibody-ku waa sheyga ka jawaab celinta difaaca aadanaha ee ka hortagga coronavirus-ga cusub.Tijaabada difaaca jirka waxay bixisaa faa'iidooyin dhowr ah marka loo eego RT-PCR.Marka hore, serological antibody wuxuu tijaabiyaa fudud oo degdeg ah.Tijaabooyinka socodka lateral ka-hortagga waxa loo isticmaali karaa goob-daryeel si loogu keeno natiijada 15 daqiiqo.Marka labaad, bartilmaameedka lagu ogaaday baaritaanka serological waa antibody, kaas oo la og yahay inuu aad uga xasilloon yahay fayraska RNA.Inta lagu jiro ururinta, rarida, kaydinta iyo tijaabinta, muunadaha shaybaadhka kahortaga jidhka ayaa guud ahaan ka xasiloon marka loo eego muunadaha RT-PCR.Marka saddexaad, sababtoo ah unugyada difaaca si siman ayaa loogu qaybiyaa wareegga dhiigga, waxaa jira kala duwanaansho muunad yar marka loo eego baaritaanka nucleic acid.Mugga muunada ee looga baahan yahay baaritaanka ka hortagga unugyada waa mid yar.Tusaale ahaan, 10 microliter oo dhiiga faraha laga muday ayaa ku filan in loo isticmaalo baaritaanka socodka dambe ee antibody.
Guud ahaan, tijaabada antibody-ka waxaa loo doortaa sidii qalab dheeri ah oo lagu ogaanayo aashitada nuclei-ka si loo hagaajiyo heerka ogaanshaha coronavirus-ka cusub inta lagu jiro koorsooyinka cudurka.Marka baaritaanka difaaca jirka lala isticmaalo baaritaanka aashitada nukliyeerka, waxay kordhin kartaa saxnaanta qiimeynta ogaanshaha COVID19 iyadoo la yareynayo natiijooyinka been-abuurka ah iyo kuwa been-abuurka ah.Hagaha hawlgalka hadda kuma talinayo in si gaar ah loo isticmaalo laba nooc oo tijaabo ah oo ah qaabka ogaanshaha madax-bannaan laakiin waa in loo isticmaalo qaab la isku daray.[2]
Jaantuska2:Fasiraadda saxda ah ee nucleic acid iyo natiijooyinka baaritaanka antibody-ka ee lagu ogaanayo caabuqa coronavirus-ka cusub
Jaantuska 3:Liming Bio-Products Co., Ltd. - Novel coronavirus IgM/IgG antibody dual test Kit (StrongStep)®SARS-CoV-2 IgM/IgG Kahortagaha Kahortagaha Degdegga ah, Immunochromatography Latex)
Jaantuska 4:Liming Bio-Products Co., Ltd. - StrongStep®Novel Coronavirus (SARS-CoV-2) Qalabka PCR-waqtiga-dhabta ah ee isku-dhafan (ogaanshaha saddexda hidde-side, habka baaritaanka fluorescent).
Fiiro gaar ah:Xirmadan aadka u xasaasiga ah, ee diyaar u ah in la isticmaalo PCR waxa lagu heli karaa qaab lyophilized ah (habka qalajinta qaboojinta) kaydinta muddada dheer.Qalabka waxa lagu rari karaa oo lagu kaydin karaa heerkulka qolka waana mid deggan muddo hal sano ah.Tuubo kasta oo premix ah waxay ka kooban tahay dhammaan reagen-yaasha looga baahan yahay kor u qaadida PCR, oo ay ku jiraan Reverse-transcriptase, Taq polymerase, primers, probes, iyo dNTPs substrates. Isticmaalayaashu waxay si fudud dib u habeyn karaan isku dhafka iyaga oo ku daraya biyaha PCR-fasalka oo ay la socdaan qaab-dhismeedka dulso aaladda PCR si aad kor ugu qaaddo
Iyada oo laga jawaabayo dillaaca cusub ee coronavirus, Liming Bio-Products Co., Ltd. waxay si dhakhso leh uga shaqeysay inay soo saarto laba qalab oo lagu baadho si ay awood ugu siiso shaybaarada caafimaadka iyo caafimaadka dadweynaha inay si dhakhso leh u baaraan caabuqa COVID-19.Xirmooyinkani aad bay ugu habboon yihiin in loo isticmaalo baadhis ballaadhan oo laga sameeyo waddamada iyo gobollada uu ka dillaacay novel coronavirus si degdeg ah ugu faafayo, iyo bixinta ogaanshaha iyo xaqiijinta caabuqa COVID-19.Xirmooyinkan waxaa loogu talagalay in lagu isticmaalo oo keliya iyadoo hoos timaada Oggolaanshaha Isticmaalka Degdegga ah ee Horay loo Ogaysiiyay (PEUA).Tijaabadu waxay ku kooban tahay shaybaarada lagu shahaadeeyay nidaamka heer qaran ama heer degmo.
Habka ogaanshaha antigen
1. Ogaanshaha antigen-ka fayraska waxa loo kala saaray isla qaybta ogaanshaha tooska ah ee ogaanshaha acid nucleic.Hababkan ogaanshaha tooska ah waxay raadiyaan caddaynta cudur-sidaha fayraska ee tijaabada waxaana loo isticmaali karaa xaqiijinta ogaanshaha.Si kastaba ha ahaatee, horumarinta xirmooyinka ogaanshaha antigen waxay u baahan tahay tayada sare ee unugyada difaaca jirka ee monoclonal oo leh xiriir adag iyo dareen sare oo awood u leh aqoonsiga iyo qabashada fayraska pathogenic.Caadi ahaan waxay qaadataa in ka badan lix bilood in la doorto oo la hagaajiyo antibody-ka monoclonal ee ku habboon in loo isticmaalo diyaarinta xirmada ogaanshaha antigen.
2. Hadda, dib-u-hawlgalayaasha si toos ah loo ogaado cudurka 'coronavirus' cusub ayaa weli ku jira cilmi-baaris iyo heer horumarineed.Sidaa darteed, ma jiro xidhmo ogaanshaha antigen-ka oo si caafimaad ahaan loo ansixiyey oo ganacsi ahaan loo helay.In kasta oo hore loo sheegay in shirkad baadhiseed oo ku taal Shenzhen ay soo saartay qalab lagu ogaanayo antigen-ka oo caafimaad ahaan lagu tijaabiyey Spain, isku halaynta tijaabada iyo saxnaanta lama xaqiijin karo sababtoo ah joogitaanka arrimaha tayada reagent.Ilaa hadda, NMPA (FDA Shiinaha oo hore u ahaan jirtay) ma aysan oggolaan xirmo kasta oo ogaanshaha antigen-ka ee isticmaalka bukaan-socodka weli.Gabagabadii, habab kala duwan oo lagu ogaanayo ayaa la sameeyay.Hab kastaa wuxuu leeyahay faa'iidooyin iyo xaddidid.Natiijooyinka habab kala duwan ayaa loo isticmaali karaa xaqiijinta iyo dhamaystirka.
3. Soo saarista xirmada tijaabada COVID-19 oo tayo leh waxay si xoogan ugu xiran tahay wanaajinta inta lagu jiro cilmi baarista iyo horumarinta.Hal qayb oo ka mid ah Liming Bio-Product Co., Ltd.xirmooyinka tijaabada ayaa looga baahan yahay inay la kulmaan heerarka wax soo saarka iyo tayada tayada adag si loo hubiyo inay bixiyaan heerarka ugu sarreeya ee waxqabadka iyo joogtaynta.Saynis yahanada jooga Liming Bio-Product Co., Ltd. waxay leeyihiin waayo-aragnimo labaatan sano ka badan xagga naqshadaynta, tijaabinta, iyo tayaynta xirmooyinka ogaanshaha fayraska si loo hubiyo heerka ugu sarreeya ee wax qabad ee qiimaynta falanqaynta.
Intii lagu guda jiray faafitaanka COVID-19, dowladda Shiinaha waxay wajahday sare u kac ah baahida weyn ee agabka ka hortagga cudurrada ee meelaha kulul ee caalamiga ah.On April 5, at shirka jaraa'id ee Golaha Gobolka Wadajirka Ka-hortagga iyo Kantaroolka Mechanism "Xoojinta Maareynta Tayada ee Qalabka Caafimaadka iyo Nidaaminta Amarka Suuqa", Jiang Fan, kormeeraha heerka koowaad ee Waaxda Ganacsiga Dibadda ee Wasaaradda Ganacsiga, ayaa yidhi, "Marka xigta, waxaan dadaalkeena diiradda saari doonaa laba dhinac, marka hore, si loo dardargeliyo taageerada sahayda caafimaad ee badan oo ay u baahan yihiin beesha caalamka, iyo sidoo kale, si kor loogu qaado ilaalinta tayada, nidaaminta, iyo maareynta badeecadaha. Waxaan ka dhigi doonaa ka qayb qaadashada Shiinaha si wadajir ah wax looga qabto cudurka faafa ee caalamiga ah iyo dhisida bulsho leh mustaqbal ay wadaagaan aadanaha.
Jaantuska 5:Liming Bio-Products Co.,Ltd's novel coronavirus reagent wuxuu helay shahaadada diiwaangelinta CE ee EU
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Houshenshan
Jaantus 6. Liming Bio-Products Co., Ltd. waxay taageertay Wuhan Vulcan (HouShenShan) Mountain Hospital si uu ula dagaallamo faafitaanka COVID-19 waxaana la guddoonsiiyay shahaado sharafeedka Laanqayrta Cas ee Wuhan.Cisbitaalka buuraleyda Wuhan Vulcan waa cisbitaalka ugu caansan Shiinaha kaas oo ku takhasusay daawaynta bukaanada daran ee COVID-19.
Maaddaama uu dillaacay novel coronavirus-ku sii fidayo adduunka oo dhan, Nanjing Liming Bio-Products Co., Ltd. Waxa ay kor u qaadaysaa taageerada iyo caawinta bulshooyinka adduunka oo dhan tignoolajiyadayada cusub si ay ula dagaallamaan khatartan caalamiga ah ee aan horay loo arag.Tijaabada degdega ah ee caabuqa COVID-19 ayaa qayb muhiim ah ka ah wax ka qabashada khatartan.Waxaan sii wadeynaa inaan wax ku biirinno si muhiim ah anagoo siinaya aalado lagu ogaanayo tayada sare leh gacmaha shaqaalaha daryeelka caafimaadka ee safka hore si dadku ay u helaan natiijooyinka baaritaanka muhiimka ah ee ay u baahan yihiin.Dadaalka Liming Bio-products Co., Ltd. ee dagaalka lagula jiro COVID-19 masiibada waa in aan ku biirino tignoolajiyadayada, khibradaheena, iyo khibradayada bulshooyinka caalamiga ah si loo dhiso bulsho caalami ah oo aayaha.
Riix dheer~Saami oo nalasoco
Iimayl: sales@limingbio.com
Website: https://limingbio.com
Waqtiga boostada: Meey-01-2020
